11 But I will bring them with a mighty hand and a stretched out arm, and smite Egypt with plagues, as before, and will destroy all the land thereof.

Woe means destruction. There have been thus far two major destructions and a third is prophesied. Applying Mark 13:35 and 2 Esdras 9:1, we can deduce that the third destruction (world war) is on the horizon. At this point in history however, only one world war had been fought

Strong's Concordance